other material
confidence high
sentiment negative
materiality 0.90
MannKind discontinues Phase 3 MNKD-101 trial for NTM lung disease after futility analysis
MANNKIND CORP
- Discontinuation based on interim analysis of first 46 participants; none showed sputum culture conversion.
- DSMB agreed with decision due to futility; no safety issues identified in any DSMB meetings.
- Company will investigate outcome and focus on advancing MNKD-102 dry powder formulation toward Phase 1.