other_material
confidence high
sentiment positive
materiality 0.75
HCW Biologics doses first patient in Phase 1 trial of HCW9302 for alopecia areata
HCW Biologics Inc.
- First patient dosed at Ohio State University Wexner Medical Center in multi-center first-in-human Phase 1 trial.
- HCW9302 is a subcutaneous IL-2 fusion molecule designed to expand Treg cells, built on the TOBI platform.
- Trial plans to enroll up to 30 patients; primary objectives are safety and determination of recommended Phase 2 dose.
- Secondary endpoints include disease response and effects on Treg cell proliferation; expansion into other autoimmune and inflammatory conditions is planned.
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