secwatch.observer — SEC 8-K summary ====================================== Issuer: Cyclerion Therapeutics, Inc. (CYCN) CIK: 0001755237 Form: 8-K Filed at: 2025-12-01T23:59:59+00:00 Accession: 0001193125-25-304067 Event type: other_material Sentiment: neutral Materiality: 0.35 Item codes: 8.01 LLM model: deepseek-v4-flash:cloud@v2 Cyclerion to receive $1M milestone if Akebia doses first patient in Phase 2 FSGS trial -------------------------------------------------------------------------------- - Akebia announced Phase 2 trial initiation for Praliciguat in FSGS; first patient dosing expected in 2026. - Under license amendment, Cyclerion is owed $1.0M upon first patient dosed in a US Phase 2 trial. - The milestone payment is not yet due as dosing has not begun. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1755237/000119312525304067/0001193125-25-304067-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1755237/000119312525304067/d48096d8k.htm HTML page: https://secwatch.observer/filing/0001193125-25-304067 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer