M&A
confidence high
sentiment positive
materiality 0.75
Repare Therapeutics Inc.: M&A transaction — Repare sells Polθ inhibitor RP-3467 to Gilead for up to $30M; Xeno deal per-share value rises to ~$2.20
Repare Therapeutics Inc.
- Gilead will pay up to $30M ($25M upfront + $5M transfer completion) for Repare's RP-3467 Polθ ATPase inhibitor program.
- Repare retains other pipeline programs including RP-1664 and lunresertib/camonsertib.
- Estimated per-share cash payment in pending Xeno acquisition increased to ~$2.20, up from prior estimate due to Gilead upfront cash.
- Asset purchase closed Dec 23, 2025; consent obtained from NYU for assignment of related license agreement.
- CEO Steve Forte noted this is Repare's third and most significant portfolio transaction in 2025.