{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-007042","form_type":"8-K","ticker":"COYA","cik":"0001835022","company_name":"Coya Therapeutics, Inc.","filed_at":"2026-01-08T23:59:59+00:00","discovered_at":"2026-05-14T18:02:36.447959+00:00","generated_at":"2026-05-16T11:14:58.215710+00:00","sec_items":["8.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Coya Therapeutics reports positive proof-of-concept study results in Frontotemporal Dementia","bullets":["9-patient open-label study of low-dose IL-2 + CTLA4-Ig showed no serious adverse events over 22 weeks.","Treg suppressive function and percentage significantly increased from week 2 through week 22.","MOCA scores stable (baseline 13.5, week 22: 14) and CDR-FTLD stable (4.8 vs 5.5), indicating no cognitive decline.","Study led by Houston Methodist Neurological Institute; funded by Peggy and Gary Edwards Endowment Fund.","Common adverse event was mild injection-site erythema (33.3%); all resolved spontaneously."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-007042","json":"https://secwatch.observer/filing/0001193125-26-007042.json","markdown":"https://secwatch.observer/filing/0001193125-26-007042.md","text":"https://secwatch.observer/filing/0001193125-26-007042.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1835022/000119312526007042/0001193125-26-007042-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1835022/000119312526007042/d39008d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T11:14:58.215710+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}