{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-008277","form_type":"8-K","ticker":"CATX","cik":"0000728387","company_name":"Perspective Therapeutics, Inc.","filed_at":"2026-01-09T23:59:59+00:00","discovered_at":"2026-05-14T18:02:37.598440+00:00","generated_at":"2026-05-16T11:07:50.642379+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Perspective Therapeutics reports 39% ORR in Cohort 2 of [212Pb]VMT-α-NET trial; safety cleared at 6.0 mCi","bullets":["Updated interim data from Phase 1/2a trial of [212Pb]VMT-α-NET in SSTR2-expressing NETs at ASCO-GI.","Objective response rate of 39% (9/23) in Cohort 2 per RECIST v1.1; 8 confirmed, 1 pending.","76% (19/25) of evaluable patients without progression and alive; deepening of best response seen in 7 patients.","DLT assessment completed for Cohort 3 (6.0 mCi); cleared to enroll more; one additional patient already treated.","No DLTs, treatment-related discontinuations, or serious renal complications across 56 patients."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-008277","json":"https://secwatch.observer/filing/0001193125-26-008277.json","markdown":"https://secwatch.observer/filing/0001193125-26-008277.md","text":"https://secwatch.observer/filing/0001193125-26-008277.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/728387/000119312526008277/0001193125-26-008277-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/728387/000119312526008277/catx-20260109.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T11:07:50.642379+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}