earnings
confidence high
sentiment positive
materiality 0.75
Ultragenyx prelim 2025 revenue $672-674M beats guidance; cash $735M; two gene therapy approvals possible in 2026
Ultragenyx Pharmaceutical Inc.
2025-FY EPS reported
-$5.83
revenue$673,000,000
- Preliminary FY2025 total revenue $672-674M, ~20% YoY, exceeding top end of guidance.
- Crysvita revenue $480-482M (17% YoY, above guidance); Dojolvi $95-97M (9% YoY, at guidance midpoint).
- Cash and investments ~$735M at year-end 2025; full Q4/FY results and 2026 guidance due Feb 2026.
- 2026 catalysts: DTX401 (GSDIa) PDUFA Q3; UX111 (MPS IIIA) BLA resubmission early 2026; GTX-102 (Angelman) Phase 3 data H2 2026.
- UX701 (Wilson disease) pivotal data H1 2026; UX143 (osteogenesis imperfecta) data presented at JPM conference.