other material
confidence high
sentiment positive
materiality 0.75
BioAge positive Phase 1 data for BGE-102: 86% hsCRP reduction, 93% normalized
BioAge Labs, Inc.
- BGE-102 achieved 86% median hsCRP reduction at Day 14 in obese patients with elevated baseline hsCRP; 93% reached <2 mg/L.
- Significant reductions in IL-6 (44%) and fibrinogen (30%) observed, indicating downstream inflammatory cascade suppression.
- BGE-102 well tolerated with no dose-limiting toxicities; favorable safety profile.
- Phase 1 completion and Phase 2a initiation in obese patients with CV risk factors expected in 1H 2026.
- Patent issued covering additional composition of matter and novel NLRP3 binding site.