---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-26-010480"
form_type: "8-K"
ticker: "ZYME"
cik: "0001937653"
company_name: "Zymeworks Inc."
filed_at: "2026-01-12T23:59:59+00:00"
generated_at: "2026-05-16T10:57:53.079065+00:00"
event_type: "other_material"
sentiment: "negative"
materiality_score: 0.8
calibrated_materiality_score: 0.8
confidence: "high"
source: SEC EDGAR
---

# Zymeworks terminates CFO, reports ~$270.6M cash; new COO and CMO appointed

## Summary
- CFO Leone Patterson terminated without cause Jan 9; CEO Kenneth Galbraith appointed interim CFO.
- Preliminary cash $270.6M as of Dec 31, 2025; expects $440M milestones from Ziihera approvals in US/EU/Japan/China.
- $125M share repurchase plan announced Nov 2025; cash runway guided beyond 2028.
- Mark Hollywood promoted to COO (base salary $525K); Brian Cherry appointed Class II director.
- CMO Jeffrey Smith retiring Jan 31; Sabeen Mekan appointed CMO effective Feb 1, 2026.

## SEC filing metadata
- accession: 0001193125-26-010480
- form_type: 8-K
- ticker: ZYME
- cik: 0001937653
- company_name: Zymeworks Inc.
- filed_at: 2026-01-12T23:59:59+00:00
- event_type: other_material
- sentiment: negative
- materiality_score: 0.8
- calibrated_materiality_score: 0.8
- confidence: high
- sec_items: 2.02, 5.02, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1937653/000119312526010480/0001193125-26-010480-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1937653/000119312526010480/d97670d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-26-010480
- JSON: https://secwatch.observer/filing/0001193125-26-010480.json
- Plain text: https://secwatch.observer/filing/0001193125-26-010480.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.