other material
confidence high
sentiment positive
materiality 0.75
Wave regains full rights to WVE-006; plans FDA accelerated approval engagement mid-2026
Wave Life Sciences Ltd.
- Regained full rights to WVE-006 (RNA editing for AATD) from GSK; no upfront payment mentioned.
- Plans to engage FDA on accelerated approval pathway; regulatory feedback expected mid-2026.
- 400 mg multidose cohort data from RestorAATion-2 on track for Q1 2026; 600 mg data expected in 2026.
- GSK collaboration continues; fourth program selected in Jan 2026; potential milestones up to $2.8B.
- Cash runway expected into Q3 2028; milestone payments from GSK not included in runway.