{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-071557","form_type":"8-K","ticker":"ALEC","cik":"0001653087","company_name":"Alector, Inc.","filed_at":"2026-02-25T23:59:59+00:00","discovered_at":"2026-05-14T18:02:35.772535+00:00","generated_at":"2026-05-16T00:20:16.029745+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"negative","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Alector Q4 net loss $37.3M ($0.34/share); revenue down 89% YoY; cash $256M","bullets":["Q4 2025 net loss $37.3M vs $2.1M in Q4 2024; full-year net loss $142.9M ($1.39/share).","Collaboration revenue fell to $6.2M in Q4 from $54.2M a year earlier; full-year revenue $21M.","Cash, equivalents and investments $256M; company expects runway at least through 2027.","Independent interim futility analysis for PROGRESS-AD Phase 2 trial of nivisnebart expected H1 2026.","ABC-led pipeline advancing: AL137 IND filing planned Q4 2026/Q1 2027; AL050 IND target 2027."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-071557","json":"https://secwatch.observer/filing/0001193125-26-071557.json","markdown":"https://secwatch.observer/filing/0001193125-26-071557.md","text":"https://secwatch.observer/filing/0001193125-26-071557.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1653087/000119312526071557/0001193125-26-071557-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1653087/000119312526071557/alec-20260225.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T00:20:16.029745+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}