{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-076530","form_type":"8-K","ticker":"XENE","cik":"0001582313","company_name":"Xenon Pharmaceuticals Inc.","filed_at":"2026-02-26T23:59:59+00:00","discovered_at":"2026-05-14T18:02:35.529896+00:00","generated_at":"2026-05-15T23:36:44.321422+00:00","sec_items":["2.02","7.01","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Xenon reports 2025 net loss of $345.9M; Phase 3 X-TOLE2 data expected in March 2026","bullets":["Net loss $345.9M in 2025 vs $234.3M in 2024; R&D expense rose to $300.9M on azetukalner Phase 3 trials.","Pro forma cash $716M (incl. $130M ATM in Q1 2026) extends runway into H2 2027.","Phase 3 X-TOLE2 topline data for azetukalner in focal onset seizures due first half of March 2026.","NDA submission for azetukalner in FOS planned H2 2026; 5 additional Phase 3 studies in epilepsy and depression enrolling.","Early-stage pipeline: Phase 1 data for XEN1701 (NaV1.7) and XEN1120 (KV7) pain candidates expected in 2026."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-076530","json":"https://secwatch.observer/filing/0001193125-26-076530.json","markdown":"https://secwatch.observer/filing/0001193125-26-076530.md","text":"https://secwatch.observer/filing/0001193125-26-076530.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1582313/000119312526076530/0001193125-26-076530-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1582313/000119312526076530/xene-20260226.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-15T23:36:44.321422+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}