secwatch.observer — SEC 8-K summary ====================================== Issuer: OPKO HEALTH, INC. (OPK) CIK: 0000944809 Form: 8-K Filed at: 2026-02-26T23:59:59+00:00 Accession: 0001193125-26-076575 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 OPKO Health Q4 revenue $148.5M, net loss $31.3M; Regeneron deal >$1B -------------------------------------------------------------------- - Q4 revenue $148.5M (down 19% YoY); net loss $31.3M ($0.04/share) vs $14.0M income in Q4 2024. - Regeneron collaboration for multispecific antibodies: upfront + milestones >$200M per program, total >$1B. - Pharmaceuticals revenue $43.7M (+17% YoY); NGENLA profit share $12.5M, Rayaldee $8.8M. - Diagnostics revenue $71.1M (down 31% YoY) on asset sale; operating loss improved to $18.3M from $21.7M. - FY 2026 guidance: total revenue $530-560M; total costs $725-750M; R&D $125-135M. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/944809/000119312526076575/0001193125-26-076575-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/944809/000119312526076575/opk-20260226.htm HTML page: https://secwatch.observer/filing/0001193125-26-076575 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer