secwatch.observer — SEC 8-K summary ====================================== Issuer: Rapport Therapeutics, Inc. (RAPP) CIK: 0002012593 Form: 8-K Filed at: 2026-03-10T23:59:59+00:00 Accession: 0001193125-26-099336 Event type: earnings Sentiment: positive Materiality: 0.80 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Rapport Therapeutics reports FY2025 net loss $111.5M, RAP-219 Phase 2 positive, Phase 3 Q2 2026 -------------------------------------------------------------------------------- - Net loss Q4 2025 $33.8M, full year $111.5M; R&D expenses $94.8M FY2025 vs $60.9M FY2024. - Cash, equivalents, short-term investments $490.5M at Dec 31, 2025; runway into H2 2029. - RAP-219 Phase 2a in focal onset seizures met primary endpoints: 77.8% median reduction in clinical seizure frequency. - Phase 3 program for RAP-219 in FOS accelerated to Q2 2026; open-label safety trial enrolling. - Entered Tenacia collaboration for Greater China: $20M upfront, up to $308M milestones plus tiered royalties. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/2012593/000119312526099336/0001193125-26-099336-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/2012593/000119312526099336/rapp-20260310.htm HTML page: https://secwatch.observer/filing/0001193125-26-099336 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer