{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-115177","form_type":"8-K","ticker":"TSHA","cik":"0001806310","company_name":"Taysha Gene Therapies, Inc.","filed_at":"2026-03-19T23:59:59+00:00","discovered_at":"2026-05-14T18:02:36.247161+00:00","generated_at":"2026-05-15T09:39:53.405353+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Taysha reports FY2025 net loss $109M; TSHA-102 pivotal trial dosing on track to complete Q2 2026","bullets":["Net loss $109.0M ($0.34/share) vs $89.3M ($0.36) in 2024; R&D expenses rose to $86.4M.","Cash $319.8M as of Dec 31, 2025; raised $50M via ATM in Q4; expects funding into 2028.","Dosed multiple Rett patients in REVEAL pivotal trial; enrollment advancing, on track to complete dosing in Q2 2026.","FDA cleared ASPIRE trial in patients aged 2 to <4 yrs; alignment on CMC and data pooling for BLA submission.","TSHA-102 generally well tolerated; no treatment-related SAEs or DLTs as of March 2026 data cutoff."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-115177","json":"https://secwatch.observer/filing/0001193125-26-115177.json","markdown":"https://secwatch.observer/filing/0001193125-26-115177.md","text":"https://secwatch.observer/filing/0001193125-26-115177.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1806310/000119312526115177/0001193125-26-115177-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1806310/000119312526115177/d46409d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-15T09:39:53.405353+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}