{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-168569","form_type":"8-K","ticker":"SABS","cik":"0001833214","company_name":"SAB Biotherapeutics, Inc.","filed_at":"2026-04-22T23:59:59+00:00","discovered_at":"2026-05-14T18:02:33.061756+00:00","generated_at":"2026-05-15T04:55:36.673008+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"SAB BIO reports positive Phase 1 SAB-142 data: C-peptide preservation, T cell exhaustion, improved glycemic control","bullets":["All 4 T1D participants on SAB-142 2.5 mg/kg preserved C-peptide; 3 of 4 achieved super responder status with C-peptide above baseline at Day 120.","SAB-142 induced CD4+ Tconv cell exhaustion (TIGIT+ levels) correlating with C-peptide preservation, consistent with rabbit ATG mechanism.","Mean CGM time in range improved from 73% at baseline to 85% at Day 120, with no increase in exogenous insulin use.","Phase 2b SAFEGUARD trial topline data expected in 2H 2027; CEO cites potential best-in-class profile for T1D."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-168569","json":"https://secwatch.observer/filing/0001193125-26-168569.json","markdown":"https://secwatch.observer/filing/0001193125-26-168569.md","text":"https://secwatch.observer/filing/0001193125-26-168569.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1833214/000119312526168569/0001193125-26-168569-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1833214/000119312526168569/sabs-20260422.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-15T04:55:36.673008+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}