secwatch.observer — SEC 8-K summary ====================================== Issuer: Fulcrum Therapeutics, Inc. (FULC) CIK: 0001680581 Form: 8-K Filed at: 2026-04-27T23:59:59+00:00 Accession: 0001193125-26-178806 Event type: earnings Sentiment: neutral Materiality: 0.75 Item codes: 1.02, 2.02, 5.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Fulcrum Therapeutics Q1 net loss $18.9M, CFO retiring, CAMP4 license terminated, pociredir trial planned H2 2026 -------------------------------------------------------------------------------- - CFO Alan Musso retiring; will stay until successor named then consultant through Feb 2027. - Terminated CAMP4 license for Diamond-Blackfan anemia program; no further milestone/royalty payments. - Q1 net loss $18.9M ($17.7M Q1 2025); cash $333.3M, runway into 2029. - Positive pociredir Phase 1b data: HbF induction, hemolysis/anemia improvements; registration-enabling trial H2 2026. - Board appointed Josh Lehrer M.D., independent, receives option for 64,000 shares at $8.08. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1680581/000119312526178806/0001193125-26-178806-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1680581/000119312526178806/fulc-20260423.htm HTML page: https://secwatch.observer/filing/0001193125-26-178806 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer