MBX Biosciences Q1 net loss $23.5M; Phase 3 canvuparatide start on track for Q3 2026

MBX Biosciences, Inc.

2026-Q1 EPS reported -$0.50

Cash, equivalents and marketable securities of $440M; expected to fund operations into 2029.
R&D expenses $18.5M (down from $22.4M YoY); G&A expenses $8.8M (up from $4.1M YoY).
Phase 3 trial of once-weekly canvuparatide for hypoparathyroidism to initiate in Q3 2026 after successful FDA End-of-Phase 2 meeting.
Appointed Mark Soued as Chief Commercial Officer; he led Alnylam's US amyloidosis business and AMVUTTRA launch.
Obesity Day on May 11 to present initial blinded MBX 4291 Phase 1 data; amycretin prodrug nomination expected this quarter.

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