earnings
confidence high
sentiment neutral
materiality 0.78
Stoke reports Q1 net loss $50M; new 4-year OLE data supports zorevunersen disease-modifying potential
Stoke Therapeutics, Inc.
2026-Q1 EPS reported
-$0.79
revenue$6,229,000
- Net loss $50.0M ($0.79/share) vs prior-year net income $112.9M; revenue $6.2M down from $158.6M due to 2025 Biogen license revenue.
- Cash $411M funded into 2028; includes $80.7M from ATM sales of 2.6M shares in Q1.
- New 4-year OLE data: durable seizure reductions, statistically significant cognition/behavior gains at 1-4 years; generally well tolerated.
- Phase 3 EMPEROR enrollment (~150 pts) expected to complete June 2026, data readout mid-2027; NDA submission planned Q1 2027.
- First patient dosed in Phase 1 OSPREY (STK-002 for ADOA); SYNGAP1 candidate selection targeted in 2026.