secwatch.observer — SEC 8-K summary ====================================== Issuer: Tectonic Therapeutic, Inc. (TECX) CIK: 0001681087 Form: 8-K Filed at: 2026-05-07T23:59:59+00:00 Accession: 0001193125-26-212069 Event type: earnings Sentiment: negative Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Tectonic Therapeutic Q1 net loss $25.2M; TX45 APEX Phase 2 enrollment near complete -------------------------------------------------------------------------------- - Net loss $25.2M in Q1 2026 vs. $15.9M in Q1 2025; R&D expense $20.9M (up $7.9M YoY). - Cash $236.9M as of Mar 31, 2026, providing runway into Q4 2028. - TX45 APEX Phase 2 in PH-HFpEF enrollment nearing completion; topline data expected late Q4 2026/early Q1 2027. - TX2100 Phase 1a in HHT ongoing; topline results expected by end of Q3 2026. - Appointed François Nader as Board Chair and Jessica Chutter as independent director. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1681087/000119312526212069/0001193125-26-212069-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1681087/000119312526212069/tecx-20260507.htm HTML page: https://secwatch.observer/filing/0001193125-26-212069 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer