---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-26-220648"
form_type: "8-K"
ticker: "SPRB"
cik: "0001683553"
company_name: "SPRUCE BIOSCIENCES, INC."
filed_at: "2026-05-13T12:05:18+00:00"
generated_at: "2026-05-13T12:17:10.690992+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Spruce Biosciences Q1 net loss $12.3M; cash $54.1M (Mar 31), $107.3M (Apr 30)

## Summary
- Net loss of $12.3M ($8.94 per share) for Q1 2026; R&D expenses $7.6M, G&A $4.4M.
- Cash $54.1M at March 31, 2026; preliminary cash $107.3M at April 30, 2026; runway into H2 2027.
- Closed $69.0M diluted public offering in April 2026; secured up to $50M term loan from Avenue Capital (Tranche 1: $15M funded).
- BLA submission for TA-ERT (MPS IIIB) on track for Q4 2026; long-term data showed durable HS reduction and cognitive stabilization.

## SEC filing metadata
- accession: 0001193125-26-220648
- form_type: 8-K
- ticker: SPRB
- cik: 0001683553
- company_name: SPRUCE BIOSCIENCES, INC.
- filed_at: 2026-05-13T12:05:18+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1683553/000119312526220648/0001193125-26-220648-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1683553/000119312526220648/sprb-20260513.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-26-220648
- JSON: https://secwatch.observer/filing/0001193125-26-220648.json
- Plain text: https://secwatch.observer/filing/0001193125-26-220648.txt

## Key facts
- Earnings Releases
  SPRUCE BIOSCIENCES, INC. reported preliminary financial results for the first quarter ended March 31, 2026.
  - Period: the first quarter ended March 31, 2026
  - Result: preliminary results
  source text: On May 13, 2026, Spruce Biosciences, Inc. (the "Company") issued a press release announcing its financial results for the first quarter ended March 31, 2026 and providing corporate updates.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1683553/000119312526220648/0001193125-26-220648-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.