other material
confidence high
sentiment positive
materiality 0.70
Whitehawk Therapeutics expands ADC pipeline with option for CPT113 in up to five new programs
Whitehawk Therapeutics, Inc.
- Option agreement with Hangzhou DAC provides access to CPT113 for up to five internally developed ADC programs, including dual-payload variations.
- DXC006 data from Hangzhou DAC accepted for oral presentation at ASCO; J&J disclosed an ADC using CPT113 at AACR.
- PTK7-directed HWK-007 completed first dose cohort at 2 mg/kg, enrolling second cohort at 4 mg/kg; MUC16-directed HWK-016 enrolling first cohort at 2.5 mg/kg.
- Phase 1 dose-escalation data for HWK-007 and HWK-016 expected in first half of 2027; IND for HWK-206 anticipated mid-2026.
- Whitehawk retains global rights and full program control for new ADCs; anticipates IND submissions for multiple programs over next 12-24 months.