---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-26-256445"
form_type: "8-K"
ticker: "GUTS"
cik: "0001572616"
company_name: "FRACTYL HEALTH, INC."
filed_at: "2026-06-04T11:05:16+00:00"
generated_at: "2026-06-04T11:10:13.887928+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.8
calibrated_materiality_score: 0.8
confidence: "high"
source: SEC EDGAR
---

# Fractyl Health reports positive 1-year REVEAL-1 data: ~78% weight maintenance post-GLP-1 with Revita.

## Summary
- Participants retained ~78% of prior GLP-1-induced weight loss at one year after single Revita procedure.
- 33% of patients continued losing weight at one year; mean weight change 5.3% (n=15) vs ~15% regain with GLP-1 withdrawal alone.
- No procedure-related serious adverse events; mild events occurred in 36% of participants, all transient.
- Next data readouts: REMAIN-1 Midpoint Cohort randomized data Q3 2026, REMAIN-1 Pivotal Cohort topline Q4 2026.

## SEC filing metadata
- accession: 0001193125-26-256445
- form_type: 8-K
- ticker: GUTS
- cik: 0001572616
- company_name: FRACTYL HEALTH, INC.
- filed_at: 2026-06-04T11:05:16+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.8
- calibrated_materiality_score: 0.8
- confidence: high
- sec_items: 7.01, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1572616/000119312526256445/0001193125-26-256445-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1572616/000119312526256445/guts-20260604.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-26-256445
- JSON: https://secwatch.observer/filing/0001193125-26-256445.json
- Plain text: https://secwatch.observer/filing/0001193125-26-256445.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.