secwatch.observer — SEC 8-K summary ====================================== Issuer: enGene Therapeutics Inc. (ENGN) CIK: 0001980845 Form: 8-K Filed at: 2026-06-15T13:14:40+00:00 Accession: 0001193125-26-270384 Event type: other_material Sentiment: negative Materiality: 0.85 Item codes: 2.02, 2.05, 5.02, 7.01, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 enGene cuts workforce ~50%, CMO and CFO resign; Q2 loss widens to $30.2M ------------------------------------------------------------------------ - Workforce reduction of ~50% to streamline ops and preserve cash; restructuring costs est. $5.7-$6.4M cash plus $4.7-$5.0M non-cash stock comp. - CFO Ryan Daws to depart July 15, 2026; Kathleen Richton appointed SVP Finance and principal financial officer. - CMO Dr. Hussein Sweiti resigned effective June 14; Dr. William Grossman named interim CMO. - Q2 net loss $30.2M ($0.43/share) vs $25.8M ($0.51/share) YoY; cash, equivalents and marketable securities $285.2M. - LEGEND Cohort 1: 54% CR at any time; awaiting 12-month durability data; BLA filing and FDA meeting planned for 2H 2026. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1980845/000119312526270384/0001193125-26-270384-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1980845/000119312526270384/engn-20260613.htm HTML page: https://secwatch.observer/filing/0001193125-26-270384 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer