secwatch.observer — SEC 8-K summary ====================================== Issuer: Jaguar Health, Inc. (JAGX) CIK: 0001585608 Form: 8-K Filed at: 2026-06-22T13:17:24+00:00 Accession: 0001193125-26-276845 Event type: other_material Sentiment: neutral Materiality: 0.70 Item codes: 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Jaguar Health explores strategic alternatives; crofelemer NDA targeted for rare intestinal failure -------------------------------------------------------------------------------- - Board initiated process to evaluate strategic alternatives including M&A, partnerships, and licensing to maximize shareholder value. - Process aligns with planned completion of clinical work for NDA submission for crofelemer in rare intestinal failure diseases. - Crofelemer reduced parenteral support by up to 37% in pediatric MVID/short bowel syndrome proof-of-concept trial. - Third-party report estimates global nutritional support market for MVID at ~$1.1B in 2026, growing to ~$1.5B by 2033. - CEO Lisa Conte to update on crofelemer program at Life Sciences Virtual Investor Forum on June 24, 2026. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1585608/000119312526276845/0001193125-26-276845-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1585608/000119312526276845/d27128d8k.htm HTML page: https://secwatch.observer/filing/0001193125-26-276845 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer