other material
confidence high
sentiment negative
materiality 0.80
Evommune EVO756 Phase 2b misses primary endpoint in CSU; development halted for that indication
Evommune, Inc.
- Phase 2b trial of EVO756 in 160 CSU patients did not meet primary endpoint of UAS7 change at 12 weeks at any dose.
- Company will cease EVO756 development for CSU but will continue evaluation in atopic dermatitis and migraine.
- Top-line Phase 2b data for EVO756 in atopic dermatitis expected Q3 2026; migraine trial screening initiated.
- Cash position supports anticipated operations through 2028; EVO301 Phase 2b for AD in planning.