{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-301464","form_type":"8-K","ticker":"QTTB","cik":"0001661998","company_name":"Q32 Bio Inc.","filed_at":"2026-07-13T11:09:59+00:00","discovered_at":"2026-07-13T11:15:00.468268+00:00","generated_at":"2026-07-13T11:15:36.622199+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.8,"calibrated_materiality_score":0.8,"confidence":"high","headline":"Q32 Bio: positive 36-week Phase 2a data for bempikibart in alopecia areata; registration trial planned H1 2027","bullets":["Mean percent reduction in SALT score from baseline of 35.3% in mITT analysis at Week 36.","40% (10/25) mITT and 30.3% (10/33) ITT achieved SALT-20; 44% achieved SALT-30 and SALT-50.","No serious adverse events or Grade 3+ treatment-related AEs; mild injection site reaction in 36.3% of patients (4% of doses).","Company paid off remaining $6.8M loan to Silicon Valley Bank on June 24, 2026; loan agreement terminated.","Plans to advance bempikibart into registration-directed program in first half of 2027."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-301464","json":"https://secwatch.observer/filing/0001193125-26-301464.json","markdown":"https://secwatch.observer/filing/0001193125-26-301464.md","text":"https://secwatch.observer/filing/0001193125-26-301464.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1661998/000119312526301464/0001193125-26-301464-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1661998/000119312526301464/d142528d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-07-13T11:15:36.622199+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}