{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-318056","form_type":"8-K","ticker":"APVO","cik":"0001671584","company_name":"Aptevo Therapeutics Inc.","filed_at":"2026-07-27T20:05:18+00:00","discovered_at":"2026-07-27T20:06:00.930073+00:00","generated_at":"2026-07-27T20:06:06.909613+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Aptevo files patent for Nectin-4 x PD-L1 dual-targeting backbone; new solid tumor strategy","bullets":["Patent filing covers proprietary Nectin-4 x PD-L1 dual-targeting backbone for solid tumors.","Backbone may be adapted into radiopharmaceuticals, T-cell engagers, and immune-based therapies.","Strategy aims to enhance tumor targeting and anti-tumor immunity by targeting both Nectin-4 and PD-L1.","Filing strengthens IP portfolio and supports platform-driven approach for multiple assets and partnerships."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-318056","json":"https://secwatch.observer/filing/0001193125-26-318056.json","markdown":"https://secwatch.observer/filing/0001193125-26-318056.md","text":"https://secwatch.observer/filing/0001193125-26-318056.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1671584/000119312526318056/0001193125-26-318056-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1671584/000119312526318056/apvo-20260727.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-07-27T20:06:06.909613+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}