secwatch.observer — SEC 8-K summary ====================================== Issuer: Seaport Therapeutics, Inc. (SPTX) CIK: 0002042347 Form: 8-K Filed at: 2026-08-03T11:03:03+00:00 Accession: 0001193125-26-329528 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Seaport Therapeutics Q2 net loss $62.6M; cash $427.3M; GlyphAllo Phase 2b on track for 1H 2027 -------------------------------------------------------------------------------- - Net loss of $62.6M for Q2 2026 vs $15.1M in Q2 2025; increase driven by one-time IPO-related stock-based compensation. - Cash, cash equivalents, and investments of $427.3M as of June 30, 2026, expected to fund operations into 2029. - Phase 2b BUOY-1 trial of GlyphAllo in MDD on track; topline data expected in 1H 2027. - Positive Phase 1 data for GlyphAgo: 6.8-fold bioavailability increase vs unmodified agomelatine; Phase 2a in GAD planned for 2H 2026. - Completed upsized IPO in May 2026 raising $260M gross proceeds; Sharon Mates appointed to board. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/2042347/000119312526329528/0001193125-26-329528-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/2042347/000119312526329528/sptx-20260803.htm HTML page: https://secwatch.observer/filing/0001193125-26-329528 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer