{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-330537","form_type":"8-K","ticker":"STOK","cik":"0001623526","company_name":"Stoke Therapeutics, Inc.","filed_at":"2026-08-03T20:05:17+00:00","discovered_at":"2026-08-03T20:07:00.222009+00:00","generated_at":"2026-08-03T20:07:18.196665+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"negative","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Stoke Therapeutics Q2 net loss $61.6M; Phase 3 EMPEROR enrollment complete at 162 patients","bullets":["Net loss of $61.6M ($0.93 per share) vs $23.5M loss in Q2 2025; revenue fell to $9.3M from $13.8M.","Cash, equivalents and marketable securities $420M (incl. $65.7M post-quarter ATM sale); funds operations to potential 2028 launch.","Phase 3 EMPEROR study of zorevunersen enrolled 162 patients; data readout expected Q3 2027.","Pre-NDA meeting with FDA scheduled H2 2026; rolling NDA submission to begin Q1 2027.","Phase 1 OSPREY study of STK-002 for ADOA: sentinel cohort dosed, initial data anticipated H1 2027."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-330537","json":"https://secwatch.observer/filing/0001193125-26-330537.json","markdown":"https://secwatch.observer/filing/0001193125-26-330537.md","text":"https://secwatch.observer/filing/0001193125-26-330537.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1623526/000119312526330537/0001193125-26-330537-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1623526/000119312526330537/stok-20260803.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-08-03T20:07:18.196665+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}