secwatch.observer — SEC 8-K summary ====================================== Issuer: Tectonic Therapeutic, Inc. (TECX) CIK: 0001681087 Form: 8-K Filed at: 2026-08-06T20:10:06+00:00 Accession: 0001193125-26-338000 Event type: earnings Sentiment: neutral Materiality: 0.50 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Tectonic Q2 net loss $22.3M; cash $227M; TX45 Phase 2 enrollment complete, IDMC recommends continuation -------------------------------------------------------------------------------- - Net loss of $22.3M for Q2 2026 vs $20.0M in Q2 2025; R&D expenses $18.0M, G&A $6.2M. - Cash and cash equivalents $227.1M as of June 30, 2026; cash runway into Q1 2029. - TX45 APEX Phase 2 trial in PH-HFpEF completed enrollment (191 patients, 137 with CpcPH); IDMC recommended continuation; topline results expected early Q1 2027. - TX2100 Phase 1a single dose cohorts completed; topline results expected by end of Q3 2026; Phase 2 planned early 2027. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1681087/000119312526338000/0001193125-26-338000-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1681087/000119312526338000/d114671d8k.htm HTML page: https://secwatch.observer/filing/0001193125-26-338000 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer