earnings
confidence high
sentiment neutral
materiality 0.60
Upstream Bio Q2 net loss $39.7M; cash $261.3M funds through 2027; Phase 3 on track
Upstream Bio, Inc.
- Net loss of $39.7M for Q2 2026 vs $40.0M year ago; R&D spend $36.1M, G&A $7.1M.
- Cash and equivalents of $261.3M as of June 30, 2026, expected to fund operations through 2027.
- Phase 3 trials in severe asthma and CRSwNP on track to initiate Q1 2027; FDA End-of-Phase 2 meetings on schedule.
- Completed enrollment in Phase 2 VENTURE COPD trial (481 participants); data expected H2 2027.
- Phase 2 data: ~80% of verekitug-treated CRSwNP patients achieved NPS improvement; ERS late-breaking data Sept 5-9.