{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-345874","form_type":"8-K","ticker":"SPRB","cik":"0001683553","company_name":"SPRUCE BIOSCIENCES, INC.","filed_at":"2026-08-12T13:05:17+00:00","discovered_at":"2026-08-12T13:06:01.364077+00:00","generated_at":"2026-08-12T13:06:11.849361+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.8,"calibrated_materiality_score":0.8,"confidence":"high","headline":"Spruce Biosciences Q2 2026: cash $96.3M, TA-ERT BLA on track for Q4, $5.5M investment","bullets":["Cash and equivalents $96.3M at Jun 30, 2026 vs $48.9M at Dec 31, 2025; runway into H2 2027.","Q2 2026 net loss $16.2M ($6.68/share); six-month net loss $28.5M ($14.96/share).","BLA for TA-ERT (MPS IIIB) expected Q4 2026; TrAnsform confirmatory study to initiate Q4 2026.","Cure Sanfilippo Foundation and National MPS Society invest combined $5.5M to fund TA-ERT Expanded Access Program.","Appointed Adrian Quartel, M.D. as CMO (Jul 27, 2026) and Jessica Cohen Pfeffer, M.D. as VP Clinical Development (Aug 3, 2026)."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-345874","json":"https://secwatch.observer/filing/0001193125-26-345874.json","markdown":"https://secwatch.observer/filing/0001193125-26-345874.md","text":"https://secwatch.observer/filing/0001193125-26-345874.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1683553/000119312526345874/0001193125-26-345874-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1683553/000119312526345874/sprb-20260812.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-08-12T13:06:11.849361+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}