Spero enters $100M ATM facility with Jefferies, terminates Cantor ATM

Spero Therapeutics, Inc.

Sale Agreement with Jefferies LLC enables up to $100M of common stock in at-the-market offerings once S-3 is effective.
Registration statement on Form S-3 for up to $300M in securities filed Aug 28, 2026; not yet effective, no sales permitted until then.
Jefferies to receive up to 3.0% of gross proceeds for shares sold under the agreement.
Terminated Cantor Fitzgerald ATM agreement effective Aug 28, 2026; no shares sold under it in FY2024 or FY2025, no penalties incurred.

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