other material
confidence high
sentiment positive
materiality 0.65
Perspective Therapeutics and Merck collaborate on PSV359 + Keytruda for FAP-α solid tumors
Perspective Therapeutics, Inc.
- Clinical collaboration with Merck (NYSE: MRK) to evaluate [212Pb]PSV359 plus Keytruda in FAP-α positive solid tumors.
- Amendment to ongoing Phase 1/2a study (NCT06710756) in NSCLC and colorectal cancer; first three monotherapy dose cohorts completed enrollment.
- Merck supplies pembrolizumab at no cost; Perspective sponsors the study.
- FAP-α expressed in majority of solid tumors; combination aims to reshape tumor microenvironment and improve outcomes.