secwatch.observer — SEC 8-K summary ====================================== Issuer: Sionna Therapeutics, Inc. (SION) CIK: 0002036042 Form: 8-K Filed at: 2026-09-14T20:10:18+00:00 Accession: 0001193125-26-390577 Event type: other_material Sentiment: neutral Materiality: 0.85 Item codes: 2.05, 5.02, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Sionna cuts workforce 46%, plans Phase 2a trial for SION-451+SION-2222 ---------------------------------------------------------------------- - Board approved restructuring cutting ~46% of workforce, retaining core clinical capabilities for SION-451 and SION-2222. - Estimated restructuring charges of ~$6.4M, including $5.3M severance and $0.7M contract close-out for SION-719. - Chief Business Officer Caroline Stark Beer terminated without cause effective Sept 15, 2026; severance benefits approved. - Stock options repriced to closing price on Sept 17, 2026 for retained employees; original price reinstated if exercised before 18 months. - Plans to advance SION-451+SION-2222 into Phase 2a proof-of-concept trial initiating Q1 2027; cash runway extended into H2 2029. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/2036042/000119312526390577/0001193125-26-390577-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/2036042/000119312526390577/d148638d8k.htm HTML page: https://secwatch.observer/filing/0001193125-26-390577 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer