{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-391280","form_type":"8-K","ticker":"VERA","cik":"0001831828","company_name":"Vera Therapeutics, Inc.","filed_at":"2026-09-15T10:45:34+00:00","discovered_at":"2026-09-15T10:50:09.558975+00:00","generated_at":"2026-09-15T10:50:15.340407+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.95,"calibrated_materiality_score":0.95,"confidence":"high","headline":"TRUTAKNA meets all endpoints in ORIGIN 3 final analysis; stabilizes eGFR, cuts progression risk 76%","bullets":["Mean eGFR change at 52 weeks: TRUTAKNA -0.1 vs placebo -5.7 mL/min/1.73m² (treatment effect 5.6, p<0.0001).","Annualized eGFR slope to 104 weeks: -0.6 vs -5.6 mL/min/1.73m²/yr (effect 5.0, p<0.0001).","Composite kidney progression events: 11 vs 38; HR 0.24 (95% CI 0.12-0.48), 76% risk reduction (p<0.0001).","No dialysis/transplant/death events in TRUTAKNA arm vs 8 on placebo through 104 weeks; safety comparable to placebo.","Over 350 patient start forms in first 10 weeks of launch; sBLA for full FDA approval planned Q4 2026."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-391280","json":"https://secwatch.observer/filing/0001193125-26-391280.json","markdown":"https://secwatch.observer/filing/0001193125-26-391280.md","text":"https://secwatch.observer/filing/0001193125-26-391280.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1831828/000119312526391280/0001193125-26-391280-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1831828/000119312526391280/d32300d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-09-15T10:50:15.340407+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}