{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-400062","form_type":"8-K","ticker":"KYTX","cik":"0001994702","company_name":"Kyverna Therapeutics, Inc.","filed_at":"2026-09-24T10:00:27+00:00","discovered_at":"2026-09-24T10:05:00.486341+00:00","generated_at":"2026-09-24T10:05:38.425399+00:00","sec_items":["7.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.8,"calibrated_materiality_score":0.8,"confidence":"high","headline":"Kyverna reports durable 1-yr SPS and gMG data; BLA on track Q4 2026","bullets":["KYSA-8 SPS (n=26): median T25FW improvement 49% at 12 mo; 92% off chronic immunotherapies; no high-grade CRS/ICANS/IEC-HS.","KYSA-6 gMG (n=7): 100% achieved clinically meaningful MG-ADL/QMG improvement at 24 wks; 57% maintained MSE; 86% off immunosuppressants.","Rolling BLA for miv-cel in SPS on track for Q4 2026 completion; gMG Phase 3 enrollment expected mid-2027.","Data to be presented at MS Toronto (Oct 21-23, 2026) and AANEM (Sept 29, 2026).","Safety profile consistent: no high-grade CRS/ICANS and no IEC-HS across both trials through 1-yr follow-up."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-400062","json":"https://secwatch.observer/filing/0001193125-26-400062.json","markdown":"https://secwatch.observer/filing/0001193125-26-400062.md","text":"https://secwatch.observer/filing/0001193125-26-400062.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1994702/000119312526400062/0001193125-26-400062-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1994702/000119312526400062/kytx-20260924.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-09-24T10:05:38.425399+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}