---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-26-402820"
form_type: "8-K"
ticker: "STOK"
cik: "0001623526"
company_name: "Stoke Therapeutics, Inc."
filed_at: "2026-09-25T20:05:49+00:00"
generated_at: "2026-10-12T13:21:54.015914+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.45
calibrated_materiality_score: 0.45
confidence: "high"
source: SEC EDGAR
---

# Stoke Therapeutics director Edward Kaye resigns; board appoints Alexander Cumbo to Class III seat

## Summary
- Edward M. Kaye, M.D. resigned as a Class III director and Research and Development Committee member effective Sept. 23, 2026; resignation was not due to any disagreement with Stoke Therapeutics.
- The board appointed Alexander (Bo) Cumbo as a Class III director effective Sept. 23, 2026, to fill Kaye's vacancy; his term expires at the 2028 annual stockholders meeting.
- Cumbo is independent under SEC and Nasdaq rules and has no Item 404(a) related-party transactions with Stoke; he entered Stoke's standard director indemnity agreement.
- Under Stoke's non-employee director compensation program, Cumbo receives a $45,000 annual cash retainer and an initial option for 39,674 shares with a target grant date fair value of about $724,000.
- The option vests in twelve substantially equal quarterly installments on each quarterly anniversary of the grant date.

## SEC filing metadata
- accession: 0001193125-26-402820
- form_type: 8-K
- ticker: STOK
- cik: 0001623526
- company_name: Stoke Therapeutics, Inc.
- filed_at: 2026-09-25T20:05:49+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.45
- calibrated_materiality_score: 0.45
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1623526/000119312526402820/0001193125-26-402820-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1623526/000119312526402820/d136438d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-26-402820
- JSON: https://secwatch.observer/filing/0001193125-26-402820.json
- Plain text: https://secwatch.observer/filing/0001193125-26-402820.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.