{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-26-413090","form_type":"8-K","ticker":"ALEC","cik":"0001653087","company_name":"Alector, Inc.","filed_at":"2026-10-05T11:00:14+00:00","discovered_at":"2026-10-05T11:05:00.245993+00:00","generated_at":"2026-10-12T14:43:43.466850+00:00","sec_items":["1.01","2.02","7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.95,"calibrated_materiality_score":0.95,"confidence":"high","headline":"Alector licenses AL050 GCase program to Genentech for $100M upfront and up to $1.17B milestones","bullets":["Alector granted Genentech exclusive worldwide rights to develop and commercialize AL050, a brain-penetrant GCase enzyme replacement therapy.","Alector receives $100 million upfront and is eligible for up to $1.17 billion in development, regulatory, and commercial milestones plus tiered royalties.","Alector exercised its Spur option and will pay Spur $15 million plus a teens percentage of Genentech milestone and other non-royalty partnering income.","Preliminary cash and marketable securities were about $138.7 million as of Sept 30, 2026, or $223.7 million pro forma after Genentech upfront and Spur payment.","The Genentech deal extends Alector's cash runway into 2029; Alector will host an R&D webinar on Oct 13, 2026 for AL137, AL164, and AL062."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-26-413090","json":"https://secwatch.observer/filing/0001193125-26-413090.json","markdown":"https://secwatch.observer/filing/0001193125-26-413090.md","text":"https://secwatch.observer/filing/0001193125-26-413090.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1653087/000119312526413090/0001193125-26-413090-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1653087/000119312526413090/alec-20260930.htm"},"model":{"generated_by":"deepseek-v4.1-flash:cloud@v2","generated_at":"2026-10-12T14:43:43.466850+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}