---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-26-417384"
form_type: "8-K"
ticker: "CATX"
cik: "0000728387"
company_name: "Perspective Therapeutics, Inc."
filed_at: "2026-10-08T10:28:19+00:00"
generated_at: "2026-10-12T15:40:25.828577+00:00"
event_type: "regulatory"
sentiment: "positive"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Perspective Therapeutics wins FDA Fast Track for PSV359 in FAP-positive solitary fibrous tumors

## Summary
- FDA granted Fast Track Designation for [212Pb]PSV359 in adults with locally advanced unresectable and/or metastatic FAP-positive solitary fibrous tumors (SFTs).
- PSV359 is an investigational FAP-targeted alpha-particle therapy using the alpha-emitting isotope 212Pb, now in an ongoing Phase 1/2a study in advanced FAP-positive solid tumors.
- Fast Track may bring more frequent FDA interactions and eligibility for rolling review, Accelerated Approval, or Priority Review if criteria are met.
- CMO Markus Puhlmann noted no approved therapies specifically target FAP-alpha; imaging of FAP expression allows patient selection for targeted alpha therapy.
- CEO Thijs Spoor called the designation an important step for the broader PSV359 program; SFT patients with unresectable/metastatic disease have limited options.

## SEC filing metadata
- accession: 0001193125-26-417384
- form_type: 8-K
- ticker: CATX
- cik: 0000728387
- company_name: Perspective Therapeutics, Inc.
- filed_at: 2026-10-08T10:28:19+00:00
- event_type: regulatory
- sentiment: positive
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/728387/000119312526417384/0001193125-26-417384-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/728387/000119312526417384/catx-20261008.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-26-417384
- JSON: https://secwatch.observer/filing/0001193125-26-417384.json
- Plain text: https://secwatch.observer/filing/0001193125-26-417384.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.