secwatch.observer — SEC 8-K summary ====================================== Issuer: Spero Therapeutics, Inc. (SPRO) CIK: 0001701108 Form: 8-K Filed at: 2026-11-10T22:30:46+00:00 Accession: 0001193125-26-455789 Event type: leadership Sentiment: neutral Materiality: 0.35 Item codes: 5.02 LLM model: deepseek-v4.1-flash:cloud@v2 Spero Therapeutics appoints William Ho to board as Patrick Vink resigns ----------------------------------------------------------------------- - Patrick Vink, M.D., resigned from Spero's board effective Nov. 10, 2026, including roles as Nominating and Corporate Governance Committee chair and Compensation Committee member. - The company said Vink's resignation was not due to any dispute or disagreement and thanked him for 11 years of service. - William Ho, M.D., Ph.D., was appointed Class II director effective Nov. 10, 2026, and will serve on the Development Committee. - Ho will receive a $40,000 annual board retainer, $5,000 committee retainer and an option for 100,000 shares vesting monthly over one year. - Ho was RAPT Therapeutics' chief medical officer from 2015 to December 2025; the filing cites RAPT's $2.2 billion acquisition by GSK finalized in March 2026. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1701108/000119312526455789/0001193125-26-455789-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1701108/000119312526455789/d196561d8k.htm HTML page: https://secwatch.observer/filing/0001193125-26-455789 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer