other material
confidence high
sentiment positive
materiality 0.55
Arcturus extends CF Foundation deal; total funding up to ~$25M for ARCT-032 CF program
Arcturus Therapeutics Holdings Inc.
- CF Foundation increases financial commitment to ~$25M to advance ARCT-032, an mRNA therapeutic for cystic fibrosis.
- Arcturus to provide $15M in matching funds; royalty rates and caps modified with option to reduce via one-time payment.
- Agreement extends prior program initiated in 2017; Phase 1b study in adults with CF planned imminently.
- ARCT-032 is mutation-agnostic and aims to express functional CFTR protein in the lung, addressing root cause of CF.