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confidence high
sentiment positive
materiality 0.65
INmune Bio announces Cell Reports publication showing XPro1595 promotes remyelination
Inmune Bio, Inc.
- Publication in Cell Reports demonstrates XPro1595 converts microglia from demyelinating to remyelinating cell.
- Study led by Hellenic Pasteur Institute; identifies solTNF as critical checkpoint for microglia polarization.
- Demyelination is core mechanism in neurodegeneration; XPro1595 targets solTNF to restore glia function.
- INmune expects top-line Phase II cognitive results in early Alzheimer's patients in first half of 2025.