other material
confidence high
sentiment positive
materiality 0.55
InMed selects IVT formulation for INM-089 in dry AMD; preclinical data shows 10x safety margin
InMed Pharmaceuticals Inc.
- Selected intravitreal (IVT) formulation for INM-089 as drug candidate for dry age-related macular degeneration (AMD).
- Preclinical studies demonstrated successful delivery at doses up to 10 times projected therapeutic level, indicating favorable PK and safety margin.
- Completed dose-ranging in vivo studies to guide dose selection for pivotal preclinical toxicology studies.
- Intravitreal injection is established method for drug delivery to back of eye; overcomes challenges of topical formulations.