other material
confidence high
sentiment neutral
materiality 0.50
INmune Bio presents MINDFuL Phase II baseline data at AD/PD 2025; topline results due June 2025
Inmune Bio, Inc.
- Poster details baseline demographics of 208 patients (44% MCI, 56% mild AD) enrolled in MINDFuL Phase II trial of XPro1595.
- 69.2% of patients are APOE ε4 carriers; 64.4% met inclusion criteria for more than one inflammation biomarker.
- Primary endpoint is change from baseline in Early and Mild Alzheimer's Cognitive Composite (EMACC) score; topline results expected June 2025.
- Patients randomized 2:1 to XPro 1.0 mg/kg or placebo once weekly for 23 weeks; screen failure rate was 72%.
- Baseline characteristics show similarity to Phase III trials; no efficacy data disclosed.