---
schema_version: "secwatch.filing_event.v1"
accession: "0001213900-25-035089"
form_type: "8-K"
ticker: "RFL"
cik: "0001713863"
company_name: "Rafael Holdings, Inc."
filed_at: "2025-04-24T23:59:59+00:00"
generated_at: "2026-05-23T07:08:20.895664+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Rafael Holdings CEO Bill Conkling to step down; Executive Chairman Howard Jonas to become CEO

## Summary
- William Conkling resigns as CEO and President effective May 31, 2025; Howard Jonas appointed CEO and President effective June 1, 2025.
- Conkling to receive consulting agreement with $100,000 annual fee and accelerated vesting of options and restricted stock; no cash severance.
- Company focuses on Trappsol Cyclo for Niemann-Pick Disease Type C1; Phase 3 TransportNPC trial 48-week interim analysis expected mid-2025.
- Conkling led merger with Cyclo Therapeutics prior to departure; Jonas previously served as CEO from 2018 to 2021.

## SEC filing metadata
- accession: 0001213900-25-035089
- form_type: 8-K
- ticker: RFL
- cik: 0001713863
- company_name: Rafael Holdings, Inc.
- filed_at: 2025-04-24T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 5.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1713863/000121390025035089/0001213900-25-035089-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1713863/000121390025035089/ea0239411-8k_rafael.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001213900-25-035089
- JSON: https://secwatch.observer/filing/0001213900-25-035089.json
- Plain text: https://secwatch.observer/filing/0001213900-25-035089.txt

## Key facts
- Executive change
  Howard Jonas was appointed as Chief Executive Officer and President at Rafael Holdings, Inc..
  - Action: appointed
  - Role: Chief Executive Officer and President
  source text: On April 23, 2025, the Company’s Board of Directors elected Howard Jonas, the Company’s Executive Chairman and Chairman of the Board, as the Company’s Chief Executive Officer and President, effective June 1, 2025.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1713863/000121390025035089/0001213900-25-035089-index.htm
- Executive change
  William Conkling resigned as Chief Executive Officer and President at Rafael Holdings, Inc..
  - Action: resigned
  - Role: Chief Executive Officer and President
  source text: On April 23, 2025, William Conkling resigned as Chief Executive Officer and President of Rafael Holdings, Inc. (the “Company”), effective May 31, 2025.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1713863/000121390025035089/0001213900-25-035089-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.