other material
confidence high
sentiment positive
materiality 0.65
Aditxt subsidiary Adimune reports positive preclinical data for ADI-100; clinical trials planned in Germany and US
Aditxt, Inc.
- Completed toxicology, bio-distribution, persistence, and antibody formation studies for ADI-100 with no safety flags.
- Ex vivo data from human patient cells showed ADI-100 down-regulates anti-GAD immune activity, supporting clinical advancement.
- IP portfolio includes 130-150 patents/applications protecting the ADI platform as a tolerance delivery system.
- Clinical studies planned: psoriasis and type 1 diabetes in Germany; stiff-person syndrome and neurological in US.
- ADI-100 aims to restore immune tolerance using apoptotic cells and modified antigen (GAD), not general immune suppression.