secwatch.observer — SEC 8-K summary ====================================== Issuer: Jasper Therapeutics, Inc. (JSPR) CIK: 0001788028 Form: 8-K Filed at: 2025-06-16T23:59:59+00:00 Accession: 0001213900-25-054465 Event type: other_material Sentiment: positive Materiality: 0.85 Item codes: 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Jasper Therapeutics: 92% complete response in 180mg cohort of briquilimab SPOTLIGHT study in CIndU -------------------------------------------------------------------------------- - 11 of 12 participants (92%) achieved complete response; 12 of 12 (100%) achieved clinical response within 8-week analysis. - Tryptase levels below lower limit of quantification in 10 of 12 (83%); no SAEs or grade 3+ AEs reported. - Response rapid: 66% achieved CR/PR by week 2; 58% maintained clinical response through week 8. - No hair/skin color changes; mild transient neutrophil drops in 6 of 12 (50%), median resolution 16 days. - Conference call and webinar on June 16, 2025 at 8:00 AM EDT to present data. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1788028/000121390025054465/0001213900-25-054465-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1788028/000121390025054465/ea0245793-8k_jasper.htm HTML page: https://secwatch.observer/filing/0001213900-25-054465 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer