other_material
confidence high
sentiment positive
materiality 0.60
InMed to present INM-901 preclinical data at AAIC 2025; long-term study shows multi-modal activity
InMed Pharmaceuticals Inc.
- Preclinical data from INM-901 program presented at Alzheimer's Association International Conference (AAIC) 2025 in Toronto.
- Long-term study in 5xFAD mouse model with advanced disease; treatment duration longer than previous studies.
- INM-901 reduced inflammatory biomarkers IFN-γ, TNF-α, IL-1β, KC-GRO, IL-2, NfL in dose-dependent manner.
- Immunohistochemistry showed dose-dependent reduction in amyloid-beta immunoreactivity and partial restoration of MAP2.
- Behavioral improvements: cognitive function, anxiety-related behavior, sensory responsiveness restored or approaching normal.
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